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Published VersionCC BY V4.0, Open Access
Journal article
Cost-effectiveness of scar management post-burn: a trial-based economic evaluation of three intervention models
Scientific Reports, Vol.12, pp.1-10
2022
PMID: 36329128
Abstract
Optimal burn scar management has the potential to markedly improve the lives of children, but can require substantial healthcare resources. The study aimed to examine the cost-effectiveness of three scar management interventions: pressure garment; topical silicone gel; combined pressure garment and topical silicone gel therapy, alongside a randomised controlled trial of these interventions. Participants were children (n = 153) referred for burn scar management following grafting, spontaneous healing after acute burn injury, or reconstructive surgery. Healthcare resource use was costed from a health service perspective (6-months post-burn time-horizon). The mean total scar management cost was lowest in the topical silicone gel group ($382.87 (95% CI $337.72, $443.29)) compared to the pressure garment ($1327.02 (95% CI $1081.46, $1659.95)) and combined intervention $1605.97 ($1077.65, $2694.23)) groups. There were no significant between-group differences in Quality Adjusted Life Year estimates. There was a 70% probability that topical silicone gel dominated pressure garment therapy (was cheaper and more effective), a 29% probability that pressure garment therapy dominated combined therapy, and a 63% probability that topical silicone gel dominated combined therapy. In conclusion, topical silicone gel was the cheaper intervention, and may be favoured in the absence of clear clinical effect favouring pressure garment therapy or a combination of these management approaches. Trial registration: ACTRN12616001100482 (prospectively registered).
Details
- Title
- Cost-effectiveness of scar management post-burn: a trial-based economic evaluation of three intervention models
- Authors
- Steven M. McPhail (Corresponding Author) - Queensland University of TechnologyJodie Wiseman - The University of QueenslandMegan Simons - Queensland Children’s HospitalRoy Kimble - Queensland Children’s HospitalZephanie Tyack - The University of Queensland
- Publication details
- Scientific Reports, Vol.12, pp.1-10
- Publisher
- Nature Publishing Group
- Date published
- 2022
- DOI
- 10.1038/s41598-022-22488-3
- ISSN
- 2045-2322
- PMID
- 36329128
- Copyright note
- This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- Data Availability
- Data are available upon request from the lead author Professor Steven McPhail if the appropriate permissions are obtained including approval by Children’s Health Queensland Human Research Ethics Committee and if the conditions for access are agreed to.
- Grant note
- SMM was supported by a NHMRC fellowship (#1090440). The work was also supported by: an Australian Government Research Training Scholarship and Children’s Hospital Foundation Top-Up Scholarship (RPCPHD0022017) to Jodie Wiseman, a research grant provided to The University of Queensland by Stratpharma, and a research grant by The University of Queensland to the Queensland University of Technology to oversee the cost-effectiveness analysis.
- Organisation Unit
- School of Health - Occupational Therapy
- Language
- English
- Record Identifier
- 991113048802621
- Output Type
- Journal article
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