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Comparison of six frailty instruments in adults with heart failure: a prospective cohort pilot study
Journal article   Open access   Peer reviewed

Comparison of six frailty instruments in adults with heart failure: a prospective cohort pilot study

Julee McDonagh, Caleb Ferguson, Roslyn Prichard, Sungwon Chang, Jane L Philips, Patricia M Davidson, Phillip J Newton and Peter S Macdonald
European Journal of Cardiovascular Nursing, Vol.22(4), pp.345-354
2023
PMID: 36289051
url
https://doi.org/10.1093/eurjcn/zvac100View
Published Version

Abstract

Heart failure frailty mortality rehospitalisation
Aim: To compare the frailty prevalence and predictive performance of six frailty instruments in adults with heart failure and determine feasibility of study methods. Methods and results: Prospective cohort pilot study. Adults aged 18 years or older with a confirmed diagnosis of heart failure in Sydney, New South Wales, Australia. The Frailty Phenotype; the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE FI); St Vincent's Frailty instrument; St Vincent's Frailty instrument plus cognition and mood; The Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale; and the Deficit Accumulation Index were compared. Multiple logistic regression was used to develop six frailty instrument models to evaluate the association between each frailty instrument and composite all cause rehospitalisation and mortality at 12 monthsOne hundred and thirty one patients were included with a mean age of 54 (± 14[SD]). Frailty prevalence ranged from 33 to 81%. All instruments except one (the FRAIL scale) appeared to signal an increased odds of rehospitalisation and or mortality, yet these results were non significant. The six frailty instrument models displayed sensitivity between 88 to 92% and C statistic values of 0.71 to 0.73, suggesting satisfactory discrimination. Conclusions: The prevalence of frailty varied across six frailty instruments yet was in the higher range despite a 'younger' heart failure cohort. Further research is required to confirm the psychometric properties of these instruments for routine clinical use in an adequately powered and more diverse heart failure cohort.

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Cardiac & Cardiovascular Systems
Nursing

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