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Collection and sterilization of large volumes of bovine serum and its use in vaccines against bovine babesiosis and anaplasmosis
Journal article   Peer reviewed

Collection and sterilization of large volumes of bovine serum and its use in vaccines against bovine babesiosis and anaplasmosis

B J Rodwell, Peter Timms and R J Parker
Australian Journal of Experimental Biology and Medical Science, Vol.58(2), pp.143-147
1980
url
https://doi.org/10.1038/icb.1980.14View
Published Version

Abstract

A method is described for the collection and sterilization of 100 1 batches of bovine serum. Serum was prepared by defibrination of 20 1 volumes of whole blood using an impeller spinning at 400-500 rev./min. After freezing and thawing the raw serum was clarified through milk filters, pre-filtered through cartridge filters and sterilized by membrane filtration. The bacteriologically sterile serum was used in vaccines against bovine babesiosis and anasplasmosis after testing indicated no toxicity for Babesia and Anaplasma.

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Medicine, Research & Experimental

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