Journal article
Cognitive interventions to enhance neural compensation in Huntington's disease
Neurodegenerative Disease Management, Vol.5(2), pp.155-164
2015
PMID: 25894879
Abstract
In Huntington's disease (HD), there is growing evidence of neural compensation during neurodegeneration, and that these processes might be modifiable by environmental factors. Cognitive intervention to improve brain function has been trialled only to a very limited extent in HD; however, it has shown promise in other neurodegenerative diseases. In this review, we discuss the evidence for the use of cognitive intervention to boost neural compensation in HD, and find it has potential to delay clinical decline, particularly if applied early in the disease process. Randomized controlled trials of cognitive intervention in HD should be implemented as a next step to gauging the efficacy of this approach to improve outcomes for those with the HD gene.
Details
- Title
- Cognitive interventions to enhance neural compensation in Huntington's disease
- Authors
- Sophie C Andrews (Author) - Monash UniversityJuan F DomÃnguez (Author) - Monash UniversityEmily-Clare Mercieca (Author) - Monash UniversityNellie Georgiou-Karistianis (Author) - Monash UniversityJulie C Stout (Author) - Monash University
- Publication details
- Neurodegenerative Disease Management, Vol.5(2), pp.155-164
- Publisher
- Future Medicine Ltd.
- DOI
- 10.2217/nmt.14.58
- ISSN
- 1758-2032
- PMID
- 25894879
- Organisation Unit
- Thompson Institute; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99659595802621
- Output Type
- Journal article
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- Clinical Neurology
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