Chlamydia genomics: providing novel insights into chlamydial biology

Nathan Bachmann; Adam Polkinghorne; Peter Timms

doi:10.1016/j.tim.2014.04.013

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Chlamydia genomics: providing novel insights into chlamydial biology

Journal article

Peer reviewed

Chlamydia genomics: providing novel insights into chlamydial biology

Nathan Bachmann, Adam Polkinghorne and Peter Timms

Trends in Microbiology, Vol.22(8), pp.464-472

2014

DOI: https://doi.org/10.1016/j.tim.2014.04.013

PMID: 24882432

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Abstract

chlamydia

genomics

host adaptation

Chlamydiaceae are obligate intracellular pathogens that have successfully evolved to colonize a diverse range of hosts. There are currently 11 described species of Chlamydia, most of which have a significant impact on the health of humans or animals. Expanding chlamydial genome sequence information has revolutionized our understanding of chlamydial biology, including aspects of their unique lifecycle, host-pathogen interactions, and genetic differences between Chlamydia strains associated with different host and tissue tropisms. This review summarizes the major highlights of chlamydial genomics and reflects on the considerable impact these have had on understanding the biology of chlamydial pathogens and the changing nature of genomics tools in the 'post-genomics' era.

Details

Title: Chlamydia genomics: providing novel insights into chlamydial biology
Authors: Nathan Bachmann (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Adam Polkinghorne (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Peter Timms (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Publication details: Trends in Microbiology, Vol.22(8), pp.464-472
Publisher: Elsevier Ltd.
Date published: 2014
DOI: 10.1016/j.tim.2014.04.013
ISSN: 0966-842X
PMID: 24882432
Grants: Understanding the origin, epidemiology and transmission threat of chlamydia infection between Australian native animals and livestock, DP130102066, Australian Research Council (Australia, Canberra) - ARC
Organisation Unit: Centre for Bioinnovation
Language: English
Record Identifier: 99449817602621
Output Type: Journal article

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