Files and links (2)
Characterization of methicillin-resistant Staphylococcus aureus strains in sewage treatment plants in Tehran, Iran277.10 kB
Published VersionCC BY V4.0, Open Access
Journal article
Characterization of methicillin-resistant Staphylococcus aureus strains in sewage treatment plants in Tehran, Iran
Journal of Water and Health, Vol.19(2), pp.216-228
2021
PMID: 33901019
Abstract
Multidrug-resistant Staphylococcus aureus strains have been commonly found in hospitals and communities causing wide ranges of infections among humans and animals. Typing of these strains is a key factor to reveal their clonal dissemination in different regions. We investigated the prevalence and dissemination of different clonal groups of S. aureus with resistance phenotype to multiple antibiotics in two sewage treatment plants (STPs) in Tehran, Iran over four sampling occasions. A total of 576 S. aureus were isolated from the inlet, sludge and outlet. Of these, 80 were identified as methicillin-resistant S. aureus (MRSA) and were further characterized using a combination of Phene Plate (PhP) typing, staphylococcal cassette chromosome mec (SCCmec), ccr types, prophage and antibiotic-resistant profiling. In all, eight common type (CT) and 13 single PhP type were identified in both STPs, with one major CT accounting for 38.8% of the MRSA strains. These strains belonged to three prophage patterns and five prophage types with SCCmec type III being the predominant type. Resistance to 11 out of the 17 antibiotics tested was significantly (P < 0.0059) higher among the MRSA isolates than methicillin-sensitive S. aureus (MSSA) strains. The persistence of the strains in samples collected from the outlet of both STPs was 31.9% for MRSA and 23.1% for MSSA. These data indicated that while the sewage treatment process, in general, is still useful for removing most MRSA populations, some strains with SCCmec type III may have a better ability to survive the STP process.
Details
- Title
- Characterization of methicillin-resistant Staphylococcus aureus strains in sewage treatment plants in Tehran, Iran
- Authors
- Fateh Rahimi (Author) - University of IsfahanMohammad Katouli (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and EngineeringMohammad R Pourshafie (Author) - Pasteur Institute of Iran
- Publication details
- Journal of Water and Health, Vol.19(2), pp.216-228
- Publisher
- I W A Publishing
- Date published
- 2021
- DOI
- 10.2166/wh.2021.247
- ISSN
- 1996-7829; 1477-8920
- PMID
- 33901019
- Copyright note
- © 2021 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/).
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99531908702621
- Output Type
- Journal article
Metrics
1 File views/ downloads
22 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Environmental Sciences
- Microbiology
- Public, Environmental & Occupational Health
- Water Resources
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites