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Characterisation of Reproduction-Associated Genes and Peptides in the Pest Land Snail, Theba pisana
Journal article   Open access   Peer reviewed

Characterisation of Reproduction-Associated Genes and Peptides in the Pest Land Snail, Theba pisana

Michael J Stewart, Tianfang Wang, Bradley Harding, Utpal Bose, Russell C Wyeth, Kenneth B Storey and Scott F Cummins
PLoS One, Vol.11(10), e0162355
2016
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https://doi.org/10.1371/journal.pone.0162355View
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Abstract

Increased understanding of the molecular components involved in reproduction may assist in understanding the evolutionary adaptations used by animals, including hermaphrodites, to produce offspring and retain a continuation of their lineage. In this study, we focus on the Mediterranean snail, Theba pisana, a hermaphroditic land snail that has become a highly invasive pest species within agricultural areas throughout the world. Our analysis of T. pisana CNS tissue has revealed gene transcripts encoding molluscan reproduction-associated proteins including APGWamide, gonadotropin-releasing hormone (GnRH) and an egg-laying hormone (ELH). ELH isoform 1 (ELH1) is known to be a potent reproductive peptide hormone involved in ovulation and egg-laying in some aquatic molluscs. Two other non-CNS ELH isoforms were also present in T. pisana (Tpi-ELH2 and Tpi-ELH3) within the snail dart sac and mucous glands. Bioactivity of a synthetic ELH1 on sexually mature T. pisana was confirmed through bioassay, with snails showing ELH1-induced egg-laying behaviours, including soil burrowing and oviposition. In summary, this study presents a detailed molecular analysis of reproductive neuropeptide genes in a land snail and provides a foundation for understanding ELH function.

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Zoology
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