Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus

Victor M Oguoma; Ezekiel U. Nwose; Ifeoma   I Ulasi; Adeseye A Akintunde; Ekene  E Chukwukelu; Philip Taderera Bwititi; Ross S. Richards; Timothy Skinner

doi:10.1186/s12889-016-3910-3

Back

Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus

Journal article

Open access

Peer reviewed

Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus

Victor M Oguoma, Ezekiel U. Nwose, Ifeoma I Ulasi, Adeseye A Akintunde, Ekene E Chukwukelu, Philip Taderera Bwititi, Ross S. Richards and Timothy Skinner

BMC Public Health, Vol.17, pp.1-9

2017

DOI: https://doi.org/10.1186/s12889-016-3910-3

PMID: 28061844

Files and links (1)

pdf

s12889-016-3910-3617.56 kBDownload View

Published VersionCC BY V4.0, Open Access

Abstract

diabetes

co-morbidity

CVD risk factors

impaired fasting glucose

Nigeria

prediabetes

Background: Diabetes is a risk factor for cardiovascular diseases (CVDs) and there are reports of increasing prevalence of prediabetes in Nigeria. This study therefore characterised CVDs risk factors in subjects with impaired fasting glucose (IFG) and diabetes. Methods: Data from 4 population-based cross-sectional studies on 2447 apparently healthy individuals from 18 - 89 years were analysed. Anthropometric, blood pressure and biochemical parameters were collected and classified. Individuals with IFG (prediabetes) and diabetes were merged each for positive cases of dyslipidaemia, high blood pressure (HBP) or obesity. Optimal Discriminant and Hierarchical Optimal Classification Tree Analysis (HO-CTA) were employed. Results: Overall prevalence of IFG and diabetes were 5.8% (CI: 4.9 - 6.7%) and 3.1% (CI: 2.4 - 3.8%), respectively. IFG co-morbidity with dyslipidaemia (5.0%; CI: 4.1 - 5.8%) was the highest followed by overweight/obese (3.1%; CI: 2.5 - 3.8%) and HBP (1.8%; CI: 1.3 - 2.4%). The predicted age of IFG or diabetes and their co-morbidity with other CVD risk factors were between 40 - 45 years. Elevated blood level of total cholesterol was the most predictive co-morbid risk factor among IFG and diabetes subjects. Hypertriglyceridaemia was an important risk factor among IFG-normocholesterolaemic-overweight/obese individuals. Conclusion: The higher prevalence of co-morbidity of CVD risk factors with IFG than in diabetes plus the similar age of co-morbidity between IFG and diabetes highlights the need for risk assessment models for prediabetes and education of individuals at risk about factors that mitigate development of diabetes and CVDs.

Details

Title: Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus
Authors: Victor M Oguoma (Corresponding Author) - Charles Darwin University
Ezekiel U. Nwose - Charles Sturt University
Ifeoma I Ulasi - University of Nigeria Teaching Hospital
Adeseye A Akintunde - Ladoke Akintola University of Technology
Ekene E Chukwukelu - University of Nigeria Teaching Hospital
Philip Taderera Bwititi - Charles Sturt University
Ross S. Richards - Charles Darwin University
Timothy Skinner - Charles Darwin University
Publication details: BMC Public Health, Vol.17, pp.1-9
Publisher: BioMed Central Ltd.
Date published: 2017
DOI: 10.1186/s12889-016-3910-3
ISSN: 1471-2458
PMID: 28061844
Copyright note: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Data Availability: Data are held at the School of Psychological and Clinical Sciences based on the provision of the ethics committee. All relevant data are within this paper.
Grant note: VMO is supported by the Prestigious International Research Training Scholarship (PIRTS) and University Postgraduate Research Scholarship (UPRS) from the Charles Darwin University (CDU), Northern Territory, Australia.
Organisation Unit: Thompson Institute
Language: English
Record Identifier: 991121850202621
Output Type: Journal article

Metrics

8 Record Views

21 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Public, Environmental & Occupational Health

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites