Journal article
Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study: International Collaboration Research Overview
North American Journal of Medical Sciences, Vol.5(11), pp.625-630
2013
PMID: 24404539
Abstract
The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are >= 18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.
Details
- Title
- Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study: International Collaboration Research Overview
- Authors
- Ezekiel U. Nwose (Corresponding Author) - Charles Darwin UniversityRoss S. Richards - Charles Darwin UniversityKester Digban - Novena UniversityPhilip Taderera Bwititi - Charles Sturt UniversityGretchen EnnisKwang Choon YeeVictor Oguoma - Honia Medical Diagnostic Laboratory (Nigeria)Selma Liberato - Menzies School of Health Research
- Publication details
- North American Journal of Medical Sciences, Vol.5(11), pp.625-630
- Publisher
- Wolters Kluwer - Medknow Publications and Media Pvt. Ltd.
- Date published
- 2013
- DOI
- 10.4103/1947-2714.122303
- ISSN
- 1947-2714
- PMID
- 24404539
- Organisation Unit
- Thompson Institute
- Language
- English
- Record Identifier
- 991121849302621
- Output Type
- Journal article
Metrics
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Endocrinology & Metabolism
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Source: InCites