Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders
Martin A Katzman, Pierre Bleau, Pierre Blier, Pratap Chokka, Kevin Kjernisted, Michael Van Ameringen, Canadian Anxiety Guidelines Initiative Group and Alain Brunet
Review guidelines recommendations anxiety disorders panic disorders agoraphobia specific phobia social anxiety disorder generalized anxiety disorder GAD obsessive-compulsive disorder OCD posttraumatic stress disorder PTSD pharmacotherapy psychotherapy special populations
Abstract Background:
Anxiety and related disorders are among the most common mental disorders, with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are under-diagnosed and under-treated.
Methods:
These guidelines were developed by Canadian experts in anxiety and related disorders through a consensus process. Data on the epidemiology, diagnosis, and treatment (psychological and pharmacological) were obtained through MEDLINE, PsycINFO, and manual searches (1980–2012). Treatment strategies were rated on strength of evidence, and a clinical recommendation for each intervention was made, based on global impression of efficacy, effectiveness, and side effects, using a modified version of the periodic health examination guidelines.
Results:
These guidelines are presented in 10 sections, including an introduction, principles of diagnosis and management, six sections (Sections 3 through 8) on the specific anxiety-related disorders (panic disorder, agoraphobia, specific phobia, social anxiety disorder, generalized anxiety disorder, obsessive-compulsive disorder, and posttraumatic stress disorder), and two additional sections on special populations (children/adolescents, pregnant/lactating women, and the elderly) and clinical issues in patients with comorbid conditions.
Conclusions:
Anxiety and related disorders are very common in clinical practice, and frequently comorbid with other psychiatric and medical conditions. Optimal management requires a good understanding of the efficacy and side effect profiles of pharmacological and psychological treatments.
Details
Title
Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders
Authors
Martin A Katzman (Corresponding Author) - University of Toronto
Pierre Bleau - McGill University
Pierre Blier - University of Ottawa
Pratap Chokka - University of Alberta
Kevin Kjernisted - University of British Columbia
Michael Van Ameringen - McMaster University
Canadian Anxiety Guidelines Initiative Group (Research Group)
Alain Brunet (Group Member) - University of the Sunshine Coast, Queensland, Thompson Institute
Publication details
BMC Psychiatry, Vol.14(Suppl 1), pp.1-83
Publisher
BioMed Central Ltd.
Date published
2014
DOI
10.1186/1471-244X-14-S1-S1
ISSN
1471-244X
PMID
25081580
Copyright note
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Data Availability
Additional file download available.
Grant note
The development and publication of these guidelines was supported by unrestricted educational grants provided by Astra Zeneca Canada, Eli-Lilly Canada, Janssen Inc., Lundbeck Canada, Pfizer Canada, Purdue Canada, Servier Canada Inc., Shire Canada, and Valeant Canada.