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Callus culture as a new approach for the production of high added value compounds in Ilex paraguariensis: genotype influence, medium optimization and compounds identification
Journal article   Open access   Peer reviewed

Callus culture as a new approach for the production of high added value compounds in Ilex paraguariensis: genotype influence, medium optimization and compounds identification

Renata Grunennvaldt, Juliana Degenhardt-Goldbach, Peter Brooks, Jessica De Cassia Tomasi, Fabricio Augusto Hansel, Trong Tran, Erik N Gomes and Cicero Deschamps
Anais da Academia Brasileira de Ciências, Vol.92(3), pp.1-16
2020
PMID: 33206796
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Callus culture as a new approach for the production of high added value compounds in Ilex paraguariensis - genotype influence medium optimization and compounds identification2.34 MBDownloadView
Published Version Open Access CC BY V4.0
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https://doi.org/10.1590/0001-3765202020181251View
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Abstract

antioxidant activity biomass accumulation plant growth regulators sucrose yerba mate
Ilex paraguariensis (yerba mate) is a native species from South America and is a rich source of bioactive compounds. There is a lack of research efforts on the phytochemical investigation of callus culture from this species. In the present study, an effort was made to optimize callus culture conditions and to identify secondary compounds. Calli were induced from 10 genotypes using leaf explants and the best genotype was selected to evaluate the effects of cytokinin types and concentrations on callus induction and biomass accumulation. The best genotype and cytokinin treatment were used to conduct one last experiment with sucrose concentrations in culture media and its effects on calli biomass, antioxidant activity and secondary compounds accumulation. Callus initiation was genotype dependent, and the 6-156-6 line had the best response. Zeatin supplemented medium showed higher callus induction rate (82%) and higher biomass accumulation after 120 days (328.2 mg). Higher biomass and secondary compounds accumulation were observed for calli on 3% sucrose medium. Antioxidant activity was not affected by sucrose concentrations. Yerba mate callus culture allowed the accumulation of chlorogenic acid, cryptochlorogenic acid, neochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid, theobromine and caffeine.

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