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Caerin 1 Peptides, the Potential Jack-of-All-Trades for the Multipple Antibiotic-Resistant Bacterial Infection Treatment and Cancer Immunotherapy624.92 kB
Published VersionCC BY V4.0, Open Access
Journal article
Caerin 1 Peptides, the Potential Jack-of-All-Trades for the Multiple Antibiotic-Resistant Bacterial Infection Treatment and Cancer Immunotherapy
BioMed Research International, Vol.2022, pp.1-11
2022
Abstract
Antibiotic resistance-related bacterial infections and cancers become huge challenges in human health in the 21 st century. A number of naturally derived antimicrobial peptides possess multiple functions in host defense, including anti-infective and anticancer activities. One of which is known as the caerin 1 family peptides. The microbicidal properties of these peptides have been long discussed. The recent studies also established the usage of two members in this family, caerin 1.1 and caerin 1.9, in antimultiple antibiotic-resistant bacteria species. It is increasingly evident that caerin 1.1 and caerin 1.9 also contain additional activities in the suppression of tumor. In this review, we briefly outline the therapeutic potentials and possible mechanism of action of caerin 1.1 and 1.9 in the treatment of multiple antibiotic-resistant bacterial infection and cancer immunotherapy.
Details
- Title
- Caerin 1 Peptides, the Potential Jack-of-All-Trades for the Multiple Antibiotic-Resistant Bacterial Infection Treatment and Cancer Immunotherapy
- Authors
- Liyin Xiao (Author) - First Affiliated Hospital of Guangdong Pharmaceutical UniversityXiaodan Yang (Author) - First Affiliated Hospital of Guangdong Pharmaceutical UniversityJunjie Li (Author) - First Affiliated Hospital of Guangdong Pharmaceutical UniversityPingping Zhang (Author) - First People's Hospital of FoshanShuxian Tang (Author) - First People's Hospital of FoshanDongmin Cao (Author) - First People's Hospital of FoshanShu Chen (Author) - First People's Hospital of FoshanHejie Li (Author) - University of the Sunshine Coast, Queensland, GeneCology Research Centre - LegacyWei Zhang (Author) - First Affiliated Hospital of Guangdong Pharmaceutical UniversityGuoqiang Chen (Author) - First People's Hospital of FoshanGuoying Ni (Author) - University of the Sunshine Coast, Queensland, GeneCology Research Centre - LegacyTianfang Wang (Author) - University of the Sunshine Coast, Queensland, GeneCology Research Centre - LegacyXiao Song Liu (Author) - First Affiliated Hospital of Guangdong Pharmaceutical University
- Publication details
- BioMed Research International, Vol.2022, pp.1-11
- Publisher
- Hindawi Limited
- Date published
- 2022
- DOI
- 10.1155/2022/7841219
- ISSN
- 2314-6133; 2314-6141
- Copyright note
- Copyright © 2022 Liyin Xiao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; GeneCology Research Centre - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99629438002621
- Output Type
- Journal article
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- Domestic collaboration
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- Web Of Science research areas
- Biotechnology & Applied Microbiology
- Medicine, Research & Experimental
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