Bipolaroids: Functional imaging in bipolar disorder

G S Malhi; Jim Lagopoulos; A M Owen; L N Yatham

doi:10.1111/j.1600-0447.2004.00413.x

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Bipolaroids: Functional imaging in bipolar disorder

Journal article

Peer reviewed

Bipolaroids: Functional imaging in bipolar disorder

G S Malhi, Jim Lagopoulos, A M Owen and L N Yatham

Acta Psychiatrica Scandinavica, Vol.110(Supplement 422), pp.46-54

2004

DOI: https://doi.org/10.1111/j.1600-0447.2004.00413.x

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Abstract

bipolar disorder

fMRI

PET

neuroimaging

depression

mania

Objective: To evaluate the literature pertaining to the use of functional magnetic resonance imaging (fMRI) in bipolar disorder research. Method: A search for papers published in English in journals from 1984 onwards was conducted using MedLine and EMBASE with the following terms: functional neuroimaging or fMRI and depression or bipolar disorder. In addition, retrieved papers and literature known to the authors was also scrutinized for further relevant reports. Results: The research findings from 26 articles are tabulated and the results from 10 articles dealing specifically with bipolar disorder are discussed in detail. Conclusion: fMRI is a useful tool for investigating bipolar disorder. Preliminary studies point to trait and state abnormalities involving structures known to be associated with the generation and modulation of emotion. The patterns of fMRI activation are different to those found in healthy subjects and patients with major depression. FMRI studies are likely to provide valuable insights into the pathophysiology of bipolar disorder..

Details

Title: Bipolaroids: Functional imaging in bipolar disorder
Authors: G S Malhi (Author) - University of New South Wales
Jim Lagopoulos (Author) - University of New South Wales
A M Owen (Author) - MCR Cognition and Brain Sciences Unit, United Kingdom
L N Yatham (Author) - University of British Columbia, Canada
Publication details: Acta Psychiatrica Scandinavica, Vol.110(Supplement 422), pp.46-54
Publisher: Wiley-Blackwell Publishing Inc.
Date published: 2004
DOI: 10.1111/j.1600-0447.2004.00413.x
ISSN: 0001-690X
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99449298902621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Psychiatry

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