Journal article
Biomarkers of oxidative stress in pregnancy complications
Biomarkers in Medicine, Vol.11(3), pp.295-306
2017
PMID: 28157383
Abstract
Pregnancy complications including pre-eclampsia, gestational-diabetes mellitus, preterm birth and intrauterine growth restriction can cause acute and chronic health problems for the mother and lead to fetal loss or dysregulation of infant physiology. The human placenta is susceptible to oxidative stress and oxidative damage in early gestation contributes to the onset of these conditions later in pregnancy. Current methods of predicting pregnancy complications are limited and although a large number of factors are associated with disease progression, few biomarkers have been used to aid in disease diagnosis early in gestation. This review discusses the detection of oxidative stress markers in biological fluids and highlights the need for further studies to validate their use in the prediction or diagnosis of pregnancy disorders.
Details
- Title
- Biomarkers of oxidative stress in pregnancy complications
- Authors
- James Sm Cuffe (Corresponding Author) - Griffith UniversityZiheng Calvin Xu (Author) - Griffith UniversityAnthony V Perkins (Author) - Griffith University
- Publication details
- Biomarkers in Medicine, Vol.11(3), pp.295-306
- Publisher
- Future Medicine Ltd.
- DOI
- 10.2217/bmm-2016-0250
- ISSN
- 1752-0371
- PMID
- 28157383
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy; School of Health
- Language
- English
- Record Identifier
- 99685298402621
- Output Type
- Journal article
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- Medicine, Research & Experimental
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