Bio-sensing with butterfly wings: Naturally occurring nano-structures for SERS-based malaria parasite detection

Natalie L Garrett; Ryo Sekine; Matthew W A Dixon; Leann Tilley; Keith R Bamberry; Bayden R Wood

doi:10.1039/c4cp04930f

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Bio-sensing with butterfly wings: Naturally occurring nano-structures for SERS-based malaria parasite detection

Journal article

Open access

Peer reviewed

Bio-sensing with butterfly wings: Naturally occurring nano-structures for SERS-based malaria parasite detection

Natalie L Garrett, Ryo Sekine, Matthew W A Dixon, Leann Tilley, Keith R Bamberry and Bayden R Wood

Physical Chemistry Chemical Physics, Vol.17(33), pp.21164-21168

2014

DOI: https://doi.org/10.1039/c4cp04930f

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Abstract

malaria

blood

Raman

SERS

Surface enhanced Raman scattering (SERS) is a powerful tool with great potential to provide improved bio-sensing capabilities. The current 'gold-standard' method for diagnosis of malaria involves visual inspection of blood smears using light microscopy, which is time consuming and can prevent early diagnosis of the disease. We present a novel surface-enhanced Raman spectroscopy substrate based on gold-coated butterfly wings, which enabled detection of malarial hemozoin pigment within lysed blood samples containing 0.005% and 0.0005% infected red blood cells.

Details

Title: Bio-sensing with butterfly wings: Naturally occurring nano-structures for SERS-based malaria parasite detection
Authors: Natalie L Garrett (Author) - Monash University
Ryo Sekine (Author) - Monash University
Matthew W A Dixon (Author) - The University of Melbourne
Leann Tilley (Author) - The University of Melbourne
Keith R Bamberry (Author) - Australian Synchrotron
Bayden R Wood (Author) - The University of Melbourne
Publication details: Physical Chemistry Chemical Physics, Vol.17(33), pp.21164-21168
Publisher: Royal Society of Chemistry
Date published: 2014
DOI: 10.1039/c4cp04930f
ISSN: 1463-9076; 1463-9084; 1463-9076
Copyright note: Copyright (c) 2015. The author's accepted version is reproduced here in accordance with the publisher's copyright policy. The final definitive version is available at: http://dx.doi.org/10.1039/c4cp04930f
Organisation Unit: University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99513772202621
Output Type: Journal article

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