Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor

Melanie J White; C Phillip Morris; Bruce R Lawford; Ross Young

doi:10.1186/1744-9081-4-54

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Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor

Journal article

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Peer reviewed

Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor

Melanie J White, C Phillip Morris, Bruce R Lawford and Ross Young

Behavioral and Brain Functions, Vol.4(1), pp.1-9

2008

DOI: https://doi.org/10.1186/1744-9081-4-54

PMCID: PMC2607297

PMID: 19025655

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Abstract

Background: The A1 allele of the ANKK1 TaqIA polymorphism (previously reported as located in the D2 dopamine receptor (DRD2) gene) is associated with reduced DRD2 density in the striatum and with clinical disorders, particularly addiction. It was hypothesized that impulsivity represents an endophenotype underlying these associations with the TaqIA and that environmental stress would moderate the strength of the gene-behavior relationship.

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Title: Behavioral phenotypes of impulsivity related to the ANKK1 gene are independent of an acute stressor
Authors: Melanie J White (Author) - Queensland University of Technology
C Phillip Morris (Author) - Queensland University of Technology
Bruce R Lawford (Author) - Queensland University of Technology
Ross Young (Author) - Queensland University of Technology
Publication details: Behavioral and Brain Functions, Vol.4(1), pp.1-9
Publisher: BioMed Central Ltd.
Date published: 2008
DOI: 10.1186/1744-9081-4-54
ISSN: 1744-9081
PMID: 19025655; PMC2607297
Copyright note: © 2008 White et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Organisation Unit: University of the Sunshine Coast, Queensland; Office of the Deputy Vice-Chancellor (Research and Innovation)
Language: English
Record Identifier: 99551005202621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Behavioral Sciences; Neurosciences

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