Babesia bovis: comparison of culture-derived parasites, non-living antigen and conventional vaccine in the protection of cattle against heterologous challenge

Peter Timms; R J Dalgliesh; D N Barry; C K Dimmock; B J Rodwell

doi:10.1111/j.1751-0813.1983.tb05874.x

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Babesia bovis: comparison of culture-derived parasites, non-living antigen and conventional vaccine in the protection of cattle against heterologous challenge

Journal article

Peer reviewed

Babesia bovis: comparison of culture-derived parasites, non-living antigen and conventional vaccine in the protection of cattle against heterologous challenge

Peter Timms, R J Dalgliesh, D N Barry, C K Dimmock and B J Rodwell

Australian Veterinary Journal, Vol.60(3), pp.75-77

1983

DOI: https://doi.org/10.1111/j.1751-0813.1983.tb05874.x

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Abstract

Twenty Bos taurus cattle were vaccinated with either live commercial Babesia bovis vaccine, live parasites from in vitro culture or non-living supernatant antigen (NLSA) derived from in vitro culture and combined with the adjuvant saponin. Heterologous strain challenge 10 weeks later indicated that cattle vaccinated with live parasites from either source were strongly protected, those given 2 doses of NLSA 2 weeks apart were partially protected, and those given one dose of NLSA were poorly protected. Enzyme immunoassay detected comparable, increasing levels of specific babesial antibody in all vaccinated cattle during the 2 to 3 weeks following vaccination, after which levels in cattle given NLSA decreased. Antibody to bovine blood group factors was detected in 4 of the 10 animals given NLSA. Titres peaked after 3 to 4 weeks and then declined rapidly.

Details

Title: Babesia bovis: comparison of culture-derived parasites, non-living antigen and conventional vaccine in the protection of cattle against heterologous challenge
Authors: Peter Timms (Author) - Queensland Department of Primary Industries
R J Dalgliesh (Author) - Queensland Department of Primary Industries
D N Barry (Author) - Queensland Department of Primary Industries
C K Dimmock (Author) - Queensland Department of Primary Industries
B J Rodwell (Author) - Queensland Department of Primary Industries
Publication details: Australian Veterinary Journal, Vol.60(3), pp.75-77
Publisher: Wiley-Blackwell Publishing Ltd.
Date published: 1983
DOI: 10.1111/j.1751-0813.1983.tb05874.x
ISSN: 0005-0423
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99450010502621
Output Type: Journal article

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