Association of Sun Exposure, Skin Colour and Body Mass Index with Vitamin D Status in Individuals Who Are Morbidly Obese

Clare F Dix; Judith D Bauer; Ian Martin; Sharon Rochester; Briony Duarte Romero; Johannes B Prins; Olivia R L Wright

doi:10.3390/nu9101094

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Association of Sun Exposure, Skin Colour and Body Mass Index with Vitamin D Status in Individuals Who Are Morbidly Obese

Journal article

Open access

Peer reviewed

Association of Sun Exposure, Skin Colour and Body Mass Index with Vitamin D Status in Individuals Who Are Morbidly Obese

Clare F Dix, Judith D Bauer, Ian Martin, Sharon Rochester, Briony Duarte Romero, Johannes B Prins and Olivia R L Wright

Nutrients, Vol.9(10), pp.1-15

2017

DOI: https://doi.org/10.3390/nu9101094

PMID: 28976930

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Abstract

vitamin D

morbid obesity

sun exposure

skin colour

biomarkers

micronutrients

Vitamin D deficiency is a common issue, particularly in obese populations, and is tested by assessing serum 25(OH)D concentrations. This study aimed to identify factors that contribute to the vitamin D status in fifty morbidly obese individuals recruited prior to bariatric surgery. Data collected included serum 25(OH)D concentrations, dietary and supplement intake of vitamin D, sun exposure measures, skin colour via spectrophotometry, and genotype analysis of several single nucleotide polymorphisms in the vitamin D metabolism pathway. Results showed a significant correlation between serum 25(OH)D concentrations and age, and serum 25(OH)D and ITAC score (natural skin colour). Natural skin colour accounted for 13.5% of variation in serum 25(OH)D, with every 10° increase in ITAC score (i.e., lighter skin) leading to a 9 nmol/L decrease in serum 25(OH)D. Multiple linear regression using age, ITAC score, and average UV index in the three months prior to testing, significantly predicted serum 25(OH)D concentrations (R2 = 29.7%). Single nucleotide polymorphisms for all vitamin D genes tested, showed lower serum 25(OH)D for those with the rare genotype compared to the common genotype; this was most pronounced for fok1 and rs4588, where those with the rare genotype were insufficient (<50 nmol/L), and those with the common genotype were sufficient (≥50 nmol/L). Assessing vitamin D status in individuals with morbid obesity requires testing of 25(OH)D, but potential risk factors for this population include natural skin colour and age.

Details

Title: Association of Sun Exposure, Skin Colour and Body Mass Index with Vitamin D Status in Individuals Who Are Morbidly Obese
Authors: Clare F Dix (Corresponding Author) - The University of Queensland
Judith D Bauer - The University of Queensland
Ian Martin - Wesley Hospital
Sharon Rochester - Wesley Hospital
Briony Duarte Romero - QIMR Berghofer Medical Research Institute
Johannes B Prins - Mater Research
Olivia R L Wright - The University of Queensland
Publication details: Nutrients, Vol.9(10), pp.1-15
Publisher: MDPI AG
Date published: 2017
DOI: 10.3390/nu9101094
ISSN: 2072-6643
PMID: 28976930
Copyright note: © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Grant note: This research was supported by The University of Queensland.
Organisation Unit: School of Health - Nutrition & Dietetics
Language: English
Record Identifier: 991066129002621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Nutrition & Dietetics

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