Journal article
Association of 25-hydroxyvitamin D and parathyroid hormone with the metabolic syndrome in black South African women
Applied Physiology, Nutrition and Metabolism, Vol.42(4), pp.413-419
2017
Abstract
The relationship between 25 hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and metabolic traits appear to differ among ethnicities and may be influenced by obesity. The aim of the study was to examine the association of serum 25(OH)D and PTH, respectively, with the metabolic syndrome (MetS) while controlling for adiposity in black women. Using a cross-sectional study design, 209 urban black women aged ≥43 years from the North West Province, South Africa, were included. Multiple regression models were used to explore the relationship between 25(OH)D, PTH and body composition. To explore the association between 25(OH)D, PTH and MetS, a separate variable was created including at least three of the MetS criteria, but excluding elevated waist circumference as a diagnostic criterion in a logistic regression model. The majority of the women (69.9%) were overweight or obese and 65.5% of the women had excessive adiposity using the age specific cut-off points for body fat percentage. All body composition variables were positively associated with PTH, while BMI and waist circumference, but not body fat % had negative associations with 25(OH)D, also after adjusting for confounders. Before and after adjusting for age, body fat, habitual physical activity, tobacco use, season of data collection and estimated glomerular filtration rate, neither 25(OH)D nor PTH showed significant associations with the MetS. Although PTH was positively and 25(OH)D was negatively associated with adiposity in black women, there was no association between either 25(OH)D or PTH and the MetS in this study population, nor did adiposity influence these relationships.
Details
- Title
- Association of 25-hydroxyvitamin D and parathyroid hormone with the metabolic syndrome in black South African women
- Authors
- Olusola Funmilayo Sotunde (Author) - North-West University, South AfricaHerculina Salome Kruger (Author) - North-West University, South AfricaHattie H Wright (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringLize Havemann-Nel (Author) - North-West University, South AfricaCarina M C Mels (Author) - University of South Africa, South AfricaChrisna Ravyse (Author) - North-West University, South AfricaMerlien Pieters (Author) - North-West University, South Africa
- Publication details
- Applied Physiology, Nutrition and Metabolism, Vol.42(4), pp.413-419
- Publisher
- N R C Research Press
- Date published
- 2017
- DOI
- 10.1139/apnm-2016-0257
- ISSN
- 1715-5312
- Copyright note
- Copyright © 2017 The Authors. Reproduced with permission.
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99451022402621
- Output Type
- Journal article
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- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Nutrition & Dietetics
- Physiology
- Sport Sciences
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