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Association between protein intake from animal and plant sources and the presence of frailty in community-dwelling Australian women
Journal article   Open access   Peer reviewed

Association between protein intake from animal and plant sources and the presence of frailty in community-dwelling Australian women

Trent Bozanich, Jack Dalla Via, Simone Radavelli-Bagatini, Cassandra Smith, Elsa Dent, Anthony Villani, Robin M Daly, Michael Tieland, Jonathan M Hodgson, Kun Zhu, …
International Journal of Food Sciences and Nutrition, Vol.Advanced access
31-Mar-2026
PMID: 41918230
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Association between protein intake from animal and plant sources and the presence of frailty in community-dwelling Australian women1.37 MBDownloadView
Published Version (Advanced Access) Open Access CC BY V4.0

Abstract

frailty index nutrition Women’s health physical frailty protein source
We investigated the cross-sectional association between total, animal and plant protein intake with the presence of a multidimensional measure of frailty in older women. Participants included 1380 community-dwelling Australian women, mean (SD) age 75.1 (2.7) years. A validated food frequency questionnaire was used to determine total, plant, and animal protein intake. Frailty was assessed using a frailty index across numerous health domains (scored 0-1, ≥0.25 indicating frailty). Cross-sectional associations were analysed using multivariable-adjusted logistic regression models. In total, 275 (19.9%) women were identified as frail. A non-linear inverse association was observed between higher intakes of total protein and the odds for frailty. Compared to lowest protein intakes (Quartile [Q]1, 0.77 g/kg BW/d), greater intakes (up to 1.66 g/kg BW/d, Q4; OR 0.51 95%CI 0.31-0.82) were associated with lower odds for frailty. Higher plant (∼0.60 g/kg BW/d [Q4 vs Q1: OR 0.35 95%CI 0.22-0.57]) and animal (up to ∼0.80 g/kg BW/d; [Q3 vs Q1: OR 0.72 95%CI 0.53-0.97] protein intakes, were associated with lower odds for frailty. Older women consuming higher total protein, including a combination of animal and plant sources, were less likely to be frail, with intakes of ∼1.1-1.6 g/kg likely to be most beneficial.

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