Journal article
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
Nucleic Acids Research, Vol.39(Supplement 1), pp.D653-D657
2011
Abstract
ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms. These proteins are of interest to a wide range of biologists due to their diverse applications in medicine, neuroscience, pharmacology, drug discovery and agriculture. ArachnoServer currently manages 1078 protein sequences, 759 nucleic acid sequences and 56 protein structures. Key features of ArachnoServer include a molecular target ontology designed specifically for venom toxins, current and historic taxonomic information and a powerful advanced search interface. The following significant improvements have been implemented in version 2.0: (i) the average and monoisotopic molecular masses of both the reduced and oxidized form of each mature toxin are provided; (ii) the advanced search feature now enables searches on the basis of toxin mass, external database accession numbers and publication date in ArachnoServer; (iii) toxins can now be browsed on the basis of their phyletic specificity; (iv) rapid BLAST searches based on the mature toxin sequence can be performed directly from the toxin card; (v) private silos can be requested from research groups engaged in venoms-based research, enabling them to easily manage and securely store data during the process of toxin discovery; and (vi) a detailed user manual is now available.
Details
- Title
- ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
- Authors
- Volker Herzig (Author) - University of QueenslandD L A Wood (Author) - University of QueenslandF Newell (Author) - University of QueenslandP A Chaumeil (Author) - University of QueenslandQ Kaas (Author) - University of QueenslandG J Binford (Author) - University of QueenslandG M Nicholson (Author) - Lewis and Clark College, United StatesD Gorse (Author) - University of QueenslandG F King (Author) - University of Queensland
- Publication details
- Nucleic Acids Research, Vol.39(Supplement 1), pp.D653-D657
- Publisher
- Oxford University Press
- Date published
- 2011
- DOI
- 10.1093/nar/gkq1058
- ISSN
- 0305-1048
- Copyright note
- Copyright © The Author(s) 2010. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99451331702621
- Output Type
- Journal article
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