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Appropriateness of red blood cell transfusions in major urban hospitals and effectiveness of an intervention
Journal article   Peer reviewed

Appropriateness of red blood cell transfusions in major urban hospitals and effectiveness of an intervention

George L Rubin, W N Schofield, Mark G Dean and Anthony P Shakeshaft
Medical Journal of Australia, Vol.175(7), pp.354-358
2001
PMID: 11700811

Abstract

Objectives: To assess the appropriateness of red blood cell (RBC) transfusions and the effectiveness of an intervention to reduce inappropriate RBC transfusions. Design: Medical record audit by hospital staff using a data form, before and after randomly allocated interventions (letter only or letter+visit). Criteria for assessing appropriateness of RBC transfusions were based on a systematic literature review. Setting: Ten major urban hospitals in Sydney, New South Wales, in 1998 and 1999. Subjects: Medical records of up to 120 patients at each hospital (n=1117). Interventions: Letter-only (5 hospitals)--results of first audit at the hospital mailed to chief executive officer of that hospital; letter+visit (5 hospitals) results of first audit at the hospital presented by the research team to a meeting of that hospital's staff, and then mailed to the chief executive officer. Main outcome measure: Proportion of RBC transfusions assessed as inappropriate. Results: At first audit, 35% of RBC transfusions were assessed as inappropriate. Small reductions in inappropriate transfusions were found at the second audit, but the change was significant only for the hospitals receiving the letter-only intervention. About 5% of patients received a single RBC unit; 40% of single-unit transfusions were inappropriate. More RBC transfusions were inappropriate in surgical patients than in those treated by other specialties. Conclusions: About a third of RBC transfusions were assessed as inappropriate. The interventions had only a small effect on transfusion appropriateness.

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