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Published VersionCC BY-NC-ND V4.0, Open Access
Journal article
Application of texture analysis in tear film surface assessment based on videokeratoscopy
Journal of Optometry, Vol.6(4), pp.185-193
2013
PMCID: PMC3880449
Abstract
Purpose:
Videokeratoscopy images can be used for the non-invasive assessment of the tear film. In this work the applicability of an image processing technique, textural-analysis, for the assessment of the tear film in Placido disc images has been investigated.
Methods:
In the presence of tear film thinning/break-up, the reflected pattern from the videokeratoscope is disturbed in the region of tear film disruption. Thus, the Placido pattern carries information about the stability of the underlying tear film. By characterizing the pattern regularity, the tear film quality can be inferred. In this paper, a textural features approach is used to process the Placido images. This method provides a set of texture features from which an estimate of the tear film quality can be obtained. The method is tested for the detection of dry eye in a retrospective dataset from 34 subjects (22-normal and 12-dry eye), with measurements taken under suppressed blinking conditions.
Results:
To assess the capability of each texture-feature to discriminate dry eye from normal subjects, the receiver operating curve (ROC) was calculated and the area under the curve (AUC), specificity and sensitivity extracted. For the different features examined, the AUC value ranged from 0.77 to 0.82, while the sensitivity typically showed values above 0.9 and the specificity showed values around 0.6. Overall, the estimated ROCs indicate that the proposed technique provides good discrimination performance.
Conclusions:
Texture analysis of videokeratoscopy images is applicable to study tear film anomalies in dry eye subjects. The proposed technique appears to have demonstrated its clinical relevance and utility.
Details
- Title
- Application of texture analysis in tear film surface assessment based on videokeratoscopy
- Authors
- David Alonso-Caneiro (Corresponding Author) - Queensland University of TechnologyDorota H. Szczesna-Iskander (Author) - Wrocław University of Science and TechnologyD. Robert Iskander (Author) - Wrocław University of Science and TechnologyScott A. Read (Author) - Queensland University of TechnologyMichael J. Collins (Author) - Queensland University of Technology
- Publication details
- Journal of Optometry, Vol.6(4), pp.185-193
- Publisher
- Colegio Nacional de Opticos Optometristas de Espana,Spanish Council of Optometry
- Date published
- 2013
- DOI
- 10.1016/j.optom.2013.07.006
- ISSN
- 1989-1342; 1888-4296
- PMID
- PMC3880449
- Copyright note
- This article is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
- Grant note
- DS-I was supported by the Young Cadre 2015 Plus, 40/PD/2012 – the project was co-financed by the European Union and the Polish state budget through the European Social Fund.
- Organisation Unit
- School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99972395502621
- Output Type
- Journal article
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