Journal article
Antimicrobial Drug Resistance and Resistance Factor Transfer among Clinical Isolates of Salmonellae in Iran
Scandinavian Journal of Infectious Diseases, Vol.22(2), pp.197-203
1990
Abstract
508 salmonella strains isolated during 1983-1986 in Tehran, Iran from cases of diarrhoea inchildren less than 5 were tested for sensitivity to 10 antimicrobial drugs and their ability to transfer theresistance determinants. Salmonella typhimurium and S. havana were most common (45.7 % and 30.9%, respectively) followed by S. typhi (2.9%) and S. larochelle (2.4%). The antimicrobial agents used were chloramphenicol (C), gentamicin (C), tetracycline (T), ampicillin (A), cephalothiu (Cf), trimethoprim-sulfamethoxazole (SXT), kanamycin (K), nalidixic acid (Na), streptomycin (S), and furoxone (F). 91 % of the salmonellae isolates contained resistance determinants, of which 89.6% were resistant to more than one agent. Strains resistant to 4-7 drugs comprised 85.6 % of the total isolates. Ampicillin resistance was found in 85.4 % and nalidixic acid in 2.7 6. 58 different patterns of resistance to the antimicrobial agents used were observed, of which C/TlA/SXT/K/S and CITIAISXTIKISICf were the most frequently encountered. 71.9 % of the resistant strains contained transferable resistanct factors and S. typhimurium had the highest rate of transfer (80.8 %). Resistance to chloramphenicol had the highest rate of transfer among the agents used (77.4%) and streptomycin the lowest (20.0 %). The pattern most frequently transferred was C/T/A/SXT/K (41.9%).
Details
- Title
- Antimicrobial Drug Resistance and Resistance Factor Transfer among Clinical Isolates of Salmonellae in Iran
- Authors
- A Farhoudi-Moghaddam (Author) - Pasteur Institute of Iran, IranMohammad Katouli (Author) - Karolinska Institute, SwedenA Jafari (Author) - Pasteur Institute of Iran, IranM Bahavar (Author) - Pasteur Institute of Iran, IranM Parsi (Author) - Pasteur Institute of Iran, IranF Malekzadeh (Author) - Tehran University, Iran
- Publication details
- Scandinavian Journal of Infectious Diseases, Vol.22(2), pp.197-203
- Publisher
- Informa Healthcare
- Date published
- 1990
- DOI
- 10.3109/00365549009037902
- ISSN
- 0036-5548
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99450297802621
- Output Type
- Journal article
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