Analysis of intraspecific variation in venoms of anthophis antarcticus death adders from South Australia

Volker Herzig; Maxie Kohler; Kai F Grund; Shane Reeve; A Ian Smith; Wayne C Hodgson

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Analysis of intraspecific variation in venoms of anthophis antarcticus death adders from South Australia

Journal article

Open access

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Analysis of intraspecific variation in venoms of anthophis antarcticus death adders from South Australia

Volker Herzig, Maxie Kohler, Kai F Grund, Shane Reeve, A Ian Smith and Wayne C Hodgson

Journal of Venom Research, Vol.4, pp.13-20

2013

PMCID: PMC3797638

PMID: 24163732

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Abstract

Medical Biochemistry and Metabolomics

Pharmacology and Pharmaceutical Sciences

death adder

Acanthophis antarcticus

venom

geographical and intraspecific variation

chick biventer cervicis nerve-muscle preparation

Intraspecific variation in venom composition and activity has been reported from a wide range of snakes. Geographical origin can be one cause for this variation and has recently been documented from Acanthophis antarcticus death adders sampled across four different Australian states. The present study examined whether a narrower sampling range of A. antarcticus from four collection sites within one Australian state (i.e., South Australia) would also exhibit variation in venom composition and/or activity. The present LC-MS results reveal marked differences in the venom composition from different collection sites. The most striking difference was the reduced venom complexity found in the only venom originating from a mallee scrub habitat in comparison to the venoms from coastal heath scrub habitats. Interestingly, the pharmacological activity of all venoms was found to be the same, independent of the collection site.

Details

Title: Analysis of intraspecific variation in venoms of anthophis antarcticus death adders from South Australia
Authors: Volker Herzig (Corresponding Author) - The University of Queensland
Maxie Kohler (Author) - Monash University
Kai F Grund (Author) - Monash University
Shane Reeve (Author) - Monash University
A Ian Smith (Author) - Monash University
Wayne C Hodgson (Author) - Monash University
Publication details: Journal of Venom Research, Vol.4, pp.13-20
Publisher: Library Publishing Media
Date published: 2013
ISSN: 2044-0324; 2044-0324
PMID: 24163732; PMC3797638
Copyright note: Copyright © The Author(s). First Published by Library Publishing Media. This is an open access article, published under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.5). This license permits non-commercial use, distribution and reproduction of the article, provided the original work is appropriately acknowledged with correct citation details
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99450834502621
Output Type: Journal article

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