Journal article
An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review
Nutrition Reviews, Vol.80(3), pp.513-524
2022
PMID: 34339515
Abstract
Lutein and zeaxanthin (L/Z), xanthophylls obtained from the diet, are deposited in the macula of the eye. The macular concentration of L/Z is quantifiable as macular pigment optical density (MPOD). The aim of this review was to critically appraise the effect on MPOD of increasing L/Z intake by dietary intervention in adults. Pubmed, Cochrane Library, Web of Science, and Cinahl were searched up to April 2020. Ten studies investigating populations with and without age-related macular degeneration were included. MPOD increased significantly in 2 of the 8 controlled studies. Studies varied largely in the prescribed dietary L/Z dosage, duration, and participant characteristics. No relationships between types of dietary L/Z interventions and MPOD response could be determined. Limited monitoring of habitual dietary L/Z intake was identified as a major limitation of all 10 studies. Habitual dietary L/Z intake should be closely monitored in future studies to account for their effects on MPOD response to dietary L/Z interventions.
Details
- Title
- An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review
- Authors
- Naomi Fitzpatrick (Corresponding Author) - University of QueenslandVeronique Chachay (Author) - University of QueenslandJoanna Bowtell (Author) - University of ExeterSarah Jackman (Author) - University of ExeterSandra Capra (Author) - School of Human Movement and Nutrition Sciences, Faculty of Health and Behavioural Sciences, The University of Queensland, Saint Lucia, Queensland, AustraliaAngela Shore (Author) - School of Medicine, College of Medicine and Health, University of Exeter, Exeter, UKDavid Briskey (Author) - University of Queensland
- Publication details
- Nutrition Reviews, Vol.80(3), pp.513-524
- Publisher
- Oxford University Press
- DOI
- 10.1093/nutrit/nuab038
- ISSN
- 1753-4887
- PMID
- 34339515
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy; School of Health - Nutrition & Dietetics
- Language
- English
- Record Identifier
- 99612008902621
- Output Type
- Journal article
Metrics
17 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Nutrition & Dietetics
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites