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An Overview on Marine Sponge-Symbiotic Bacteria as Unexhausted Sources for Natural Product Discovery
Journal article   Open access   Peer reviewed

An Overview on Marine Sponge-Symbiotic Bacteria as Unexhausted Sources for Natural Product Discovery

Candice M Brinkmann, Amberlee Marker and D Ipek Kurtboke
Diversity, Vol.9(4), 40
2017
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Published VersionPDF - Published Version (Open Access)CC BY V4.0 Open Access
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https://doi.org/10.3390/d9040040View
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Abstract

marine symbiotic bacteria sponge symbionts genomic advances metagenomics marine biodiscovery marine biotechnology
Microbial symbiotic communities of marine macro-organisms carry functional metabolic profiles different to the ones found terrestrially and within surrounding marine environments. These symbiotic bacteria have increasingly been a focus of microbiologists working in marine environments due to a wide array of reported bioactive compounds of therapeutic importance resulting in various patent registrations. Revelations of symbiont-directed host specific functions and the true nature of host-symbiont interactions, combined with metagenomic advances detecting functional gene clusters, will inevitably open new avenues for identification and discovery of novel bioactive compounds of biotechnological value from marine resources. This review article provides an overview on bioactive marine symbiotic organisms with specific emphasis placed on the sponge-associated ones and invites the international scientific community to contribute towards establishment of in-depth information of the environmental parameters defining selection and acquisition of true symbionts by the host organisms.

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Biodiversity Conservation
Ecology

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