Journal article
Amphetamine psychosis: A model for studying the onset and course of psychosis
Medical Journal of Australia, Vol.190(4, Supplement 4), pp.S22-S25
2009
Abstract
• The aetiology of schizophrenia remains complex, although proposed models have identified genetic markers and environmental pathogens as important risk factors. • Researchers have found no large-effect or unique genetic elements, and only a small number of putative environmental agents have been identified. • Use of amphetamine-type stimulants (ATSs) is an exemplar environmental pathogen, as it is known to trigger schizophrenia-like illness and other psychotic and manic episodes. • To date, the ATS model of illness onset has been under-utilised. It has the potential to reveal key neurobiological elements of schizophrenia and related psychoses. • The model proposed here has the capacity to inform detection of those at risk of ATS-related psychoses, and therefore help develop early intervention strategies. • It is possible that the same approach may be used in young people known to be at risk of schizophrenia and related disorders, by informing models that involve other environmental or genetic risks.
Details
- Title
- Amphetamine psychosis: A model for studying the onset and course of psychosis
- Authors
- Daniel F Hermens (Author) - University of SydneyD I Lubman (Author) - University of SydneyP B Ward (Author) - University of SydneyS L Naismith (Author) - University of SydneyI B Hickie (Author) - University of Sydney
- Publication details
- Medical Journal of Australia, Vol.190(4, Supplement 4), pp.S22-S25
- Publisher
- Australasian Medical Publishing Company Pty. Ltd.
- Date published
- 2009
- DOI
- 10.5694/j.1326-5377.2009.tb02370.x
- ISSN
- 0025-729X
- Organisation Unit
- University of the Sunshine Coast, Queensland; Thompson Institute
- Language
- English
- Record Identifier
- 99451166502621
- Output Type
- Journal article
Metrics
336 Record Views