Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set

Zachary Woodward; Peter R Brooks; Bernadette Morris-Smith; Marianne Wallis; Steven M Ogbourne

doi:10.1007/s11095-018-2409-2

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Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set

Journal article

Open access

Peer reviewed

Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set

Zachary Woodward, Peter R Brooks, Bernadette Morris-Smith, Marianne Wallis and Steven M Ogbourne

Pharmaceutical Research, Vol.35(6), 121

2018

DOI: https://doi.org/10.1007/s11095-018-2409-2

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Abstract

active pharmaceutical ingredient

adsorption

drug delivery

drug product

intravenous

Interactions between a pharmaceutical drug and its delivery device can result in changes in drug concentration and leachable contamination. Flucloxacillin, amiodarone and cyclosporin were investigated for drug concentration changes and leachable contamination after delivery through an intravenous administration set.

Details

Title: Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set
Authors: Zachary Woodward (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Peter R Brooks (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Bernadette Morris-Smith (Author) - Sunshine Coast University Hospital
Marianne Wallis (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Steven M Ogbourne (Corresponding Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Publication details: Pharmaceutical Research, Vol.35(6), 121; 7
Publisher: Springer New York LLC
Date published: 2018
DOI: 10.1007/s11095-018-2409-2
ISSN: 0724-8741; 0724-8741
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Nursing, Midwifery and Paramedicine - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99451403402621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Chemistry, Multidisciplinary; Pharmacology & Pharmacy

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