Journal article
Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable haemophilus influenzae
Clinical and Vaccine Immunology, Vol.21(2), pp.250-252
2014
Abstract
Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significance, as protein D and hpd represent important NTHi vaccine antigen and diagnostic targets, respectively. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Details
- Title
- Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable haemophilus influenzae
- Authors
- H C Smith-Vaughan (Author) - Charles Darwin UniversityA B Chang (Author) - Charles Darwin UniversityDerek S Sarovich (Author) - Charles Darwin UniversityR L Marsh (Author) - Charles Darwin UniversityK Grimwood (Author) - Royal Children's HospitalA J Leach (Author) - Charles Darwin UniversityP S Morris (Author) - Charles Darwin UniversityErin P Price (Author) - Charles Darwin University
- Publication details
- Clinical and Vaccine Immunology, Vol.21(2), pp.250-252
- Publisher
- American Society for Microbiology
- Date published
- 2014
- DOI
- 10.1128/CVI.00632-13
- ISSN
- 1556-6811
- Organisation Unit
- University of the Sunshine Coast, Queensland; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99450422202621
- Output Type
- Journal article
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- Domestic collaboration
- Web Of Science research areas
- Immunology
- Infectious Diseases
- Microbiology
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