Logo image
Back
Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes
Journal article   Peer reviewed

Abnormal Right Ventricular Tissue Velocities After Repair of Congenital Heart Disease-Implications for Late Outcomes

R Puranik, Kim Greaves, R E Hawker, L A Pressley, P J Robinson and D S Celermajer
Heart, Lung and Circulation, Vol.16(4), pp.295-299
2007
DOI: https://doi.org/10.1016/j.hlc.2007.02.084
url
https://doi.org/10.1016/j.hlc.2007.02.084View
Published Version

Abstract

myocardial velocity congenital heart disease right ventricle
Background: Although repair of Tetralogy of Fallot (TOF) and transposition of the great arteries (TGA) has facilitated survival into adulthood, many survivors have residual haemodynamic abnormalities, including exercise intolerance and late right ventricular (RV) failure. Methods: We studied 40 asymptomatic adult subjects (31.3±1.5 years) after congenital heart disease (CHD) surgery during childhood, using tissue Doppler echocardiography (TDE). We compared systolic (S?) and diastolic (E? for early filling) RV and LV velocities, with 40 age matched controls (29.5±1.0 years). Results: Both RV S? and E? velocities were significantly slower in the CHD group compared to controls (6.3±0.4 cm/s vs. 9.3±0.3 cm/s; 8.5±0.5 cm/s vs. 10.9±0.4 cm/s, respectively, p < 0.001 for both). By contrast, LV S? and E? velocities were similar in both groups. Interestingly, in 50% of CHD subjects where RV function was reported as 'normal', both RV S? and E? velocities were significantly slower compared with controls (6.5±0.6 cm/s vs. 9.3±0.3 cm/s, p < 0.0001 and 9.4±0.7 cm/s vs. 10.9±0.4 cm/s, p < 0.05 respectively). Conclusions: RV S? and E? velocities are frequently abnormal in asymptomatic survivors of TOF and TGA repair, even where RV function appears 'normal'. Hence TDE during follow up may be a sensitive means of detecting pre-clinical abnormalities in RV performance. © 2007 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand.

Details

Metrics

444 Record Views
Logo image