A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression

Adem T. Can; Daniel F. Hermens; Jim Lagopoulos

doi:10.1002/ccr3.6675

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A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression

Journal article

Open access

Peer reviewed

A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression

Adem T. Can, Daniel F. Hermens and Jim Lagopoulos

Clinical Case Reports, Vol.10(12), pp.1-6

2022

DOI: https://doi.org/10.1002/ccr3.6675

PMCID: PMC9748241

PMID: 36523376

Appears in Thompson Institute Research Collection

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Abstract

Case Report

depression

ketamine

MADRS

NMDA

suicidality

treatment?resistant

Ketamine

Thompson Institute Special Collection

Numerous studies have demonstrated that low‐dose subanesthetic intravenous ketamine infusion treatment leads to rapid improvement of treatment‐resistant depression. The following case report describes the use of a very low‐dose subcutaneous ketamine as a form of maintenance in a patient with severe treatment‐resistant depression using a retrospective chart review. Subcutaneous ketamine can be a practical, affordable, and safe technique for treatment‐resistant depression as both acute and maintenance treatment. We describe a titration‐up method for effective and tolerable dosing based on the clinical response.

Details

Title: A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression
Authors: Adem T. Can (Author) - University of the Sunshine Coast, Queensland, Thompson Institute
Daniel F. Hermens (Author) - University of the Sunshine Coast, Queensland, Thompson Institute
Jim Lagopoulos (Corresponding Author) - University of the Sunshine Coast, Queensland, Thompson Institute
Publication details: Clinical Case Reports, Vol.10(12), pp.1-6
Publisher: John Wiley and Sons Ltd.
Date published: 2022
DOI: 10.1002/ccr3.6675
ISSN: 2050-0904
PMID: 36523376; PMC9748241
Copyright note: © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Organisation Unit: Thompson Institute; Forest Research Institute
Language: English
Record Identifier: 99695748502621
Output Type: Journal article

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