A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?

Michelle D Miller; Alison Yaxley; Anthony Villani; Lynne Cobiac; Robert Fraesr; Leslie Cleland; Michael James; Maria Crotty

doi:10.1186/1471-2318-10-76

$A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?$

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A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?

Michelle D Miller, Alison Yaxley, Anthony Villani, Lynne Cobiac, Robert Fraesr, Leslie Cleland, Michael James and Maria Crotty

BMC Geriatrics, Vol.10, 76

2010

DOI: https://doi.org/10.1186/1471-2318-10-76

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Abstract

Clinical Sciences

frailty index

rest dnergy expenditure

proximal femoral fracture

project personnel

Simplify Nutrition Appetite Questionnaire

Proximal femoral fractures are associated with increased morbidity and mortality. Pre-existing malnutrition and weight loss amongst this patient group is of primary concern, with conventional nutrition support being largely ineffective. The inflammatory response post proximal femoral fracture surgery and the subsequent risk of cachexia may explain the inability of conventional high energy high protein management to produce an anabolic response amongst these patients. Omega-3 fatty acids derived from fish oils have been extensively studied for their anti-inflammatory benefits. Due to their anti-inflammatory properties, the benefit of fish oil combined with individualized nutrition support amongst proximal femoral fracture patients post surgery is an attractive potential therapeutic strategy. The aim of the ATLANTIC trial is to assess the potential benefits of an anti-inflammatory dose of fish oil within the context of a 12 week individualised nutrition program, commencing seven days post proximal femoral fracture surgery.

Details

Title: A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?
Authors: Michelle D Miller (Author) - Flinders University
Alison Yaxley (Author) - Flinders University
Anthony Villani (Author) - Flinders University
Lynne Cobiac (Author) - Flinders University
Robert Fraesr (Author) - Flinders University
Leslie Cleland (Author) - Royal Adelaide Hospital
Michael James (Author) - Royal Adelaide Hospital
Maria Crotty (Author) - Flinders University
Publication details: BMC Geriatrics, Vol.10, 76; 10
Publisher: BioMed Central Ltd.
Date published: 2010
DOI: 10.1186/1471-2318-10-76
ISSN: 1471-2318; 1471-2318
Copyright note: Copyright © 2010 Miller et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99451440402621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Geriatrics & Gerontology; Gerontology

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