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A simple one pot procedure for the generation of homoallylic alcohols from acetals and amino acids
Journal article   Peer reviewed

A simple one pot procedure for the generation of homoallylic alcohols from acetals and amino acids

A McCluskey, D M Mayer and David James Young
Tetrahedron Letters, Vol.38(29), pp.5217-5218
1997
url
https://doi.org/10.1016/S0040-4039(97)01106-4View
Published Version

Abstract

Organic Chemistry Medicinal and Biomolecular Chemistry acetal derivative allyl alcohol amino acid trifluoroacetic acid
Treatment of acetals (1 and 2) and amino acetals (3-5) with either trifluoroacetic acid (TFA) or silica gel followed by tetraallyltin gave excellent yields of the corresponding homoallylic alcohols (68 - 100%).

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Domestic collaboration
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Chemistry, Organic

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