A matter of motion or an emotional matter? Management of depression in Parkinson's disease

Jim Lagopoulos; G S Malhi; B Ivanovski; C M Cahill; J G L Morris

doi:10.1586/14737175.5.6.803

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A matter of motion or an emotional matter? Management of depression in Parkinson's disease

Journal article

Peer reviewed

A matter of motion or an emotional matter? Management of depression in Parkinson's disease

Jim Lagopoulos, G S Malhi, B Ivanovski, C M Cahill and J G L Morris

Expert Review of Neurotherapeutics, Vol.5(6), pp.803-810

2005

DOI: https://doi.org/10.1586/14737175.5.6.803

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Abstract

antidepressant

depression

electroconvulsive therapy

Parkinson's disease

psychomotor slowing

serotonin

transcranial magnetic stimulation

Depression is one of the most frequent comorbidities occurring in Parkinson's disease, affecting up to 50% of patients. Depression is associated with severe negative symptoms and has been shown to contribute to an increased rate of decline of both cognitive and motor function, profoundly impacting on the patient's quality of life. The symptoms of depression overlap with the motor features of Parkinson's disease, making detection difficult. Moreover, the lack of specialized screening tools means that depression remains undiagnosed and untreated in a high percentage of patients. However, depression in Parkinson's disease, when identified early, can be effectively treated with a variety of antidepressant medications, improving quality of life and preserving daily function. The focus of this review is to provide an overview of current knowledge regarding depression in Parkinson's disease, followed by a practical discussion addressing the issues of the detection, diagnosis and treatment. © 2005 Future Drugs Ltd.

Details

Title: A matter of motion or an emotional matter? Management of depression in Parkinson's disease
Authors: Jim Lagopoulos (Author) - University of New South Wales
G S Malhi (Author) - University of New South Wales
B Ivanovski (Author) - University of New South Wales
C M Cahill (Author) - University of New South Wales
J G L Morris (Author) - University of Sydney
Publication details: Expert Review of Neurotherapeutics, Vol.5(6), pp.803-810
Publisher: Taylor & Francis Ltd.
Date published: 2005
DOI: 10.1586/14737175.5.6.803
ISSN: 1473-7175
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99449376502621
Output Type: Journal article

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