A Study of the Genetic and Environmental Etiology of Stuttering in a Selected Twin Sample

S Felsenfeld; K M Kirk; G Zhu; Dixie J Statham; M C Neale; N G Martin

doi:10.1023/A:1002765620208

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A Study of the Genetic and Environmental Etiology of Stuttering in a Selected Twin Sample

Journal article

Peer reviewed

A Study of the Genetic and Environmental Etiology of Stuttering in a Selected Twin Sample

S Felsenfeld, K M Kirk, G Zhu, Dixie J Statham, M C Neale and N G Martin

Behavior Genetics, Vol.30(5), pp.359-366

2000

DOI: https://doi.org/10.1023/A:1002765620208

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Abstract

Psychology

twins

stuttering

speech disorder

bivariate analysis

ascertainment bias

Stuttering is a developmental disorder of speech production that usually emerges in childhood. In this study, a large population-based twin sample from the Australian Twin Registry (1567 pairs and 634 singles aged 17-29 years) was screened to identify twin pairs in which one or both members reported themselves to be affected by stuttering. Telephone interview-based diagnoses were obtained for 457 of these individuals (self-reported affected cases, cotwins, and controls) to determine whether the self-report was correct. To correct for ascertainment bias we carried out a bivariate analysis of the final diagnosis in the selected sample with the screening item in the full sample, using the categorical raw data option of Mx 1.47c. After correcting for ascertainment bias, approximately 70% (95% confidence interval: 39-86%) of the variance in liability to stuttering was found to be attributable to additive genetic effects, with the remainder due to nonshared environmental effects.

Details

Title: A Study of the Genetic and Environmental Etiology of Stuttering in a Selected Twin Sample
Authors: S Felsenfeld (Author) - Duquesne University
K M Kirk (Author) - Queensland Institute of Medical Research
G Zhu (Author) - Queensland Institute of Medical Research
Dixie J Statham (Author) - Queensland Institute of Medical Research
M C Neale (Author) - Virginia Commonwealth University
N G Martin (Author) - Queensland Institute of Medical Research
Publication details: Behavior Genetics, Vol.30(5), pp.359-366
Publisher: Springer New York LLC
Date published: 2000
DOI: 10.1023/A:1002765620208
ISSN: 0001-8244
Organisation Unit: School of Social Sciences - Legacy; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99449878302621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Behavioral Sciences; Genetics & Heredity; Psychology, Multidisciplinary

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