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A Review on Cerebral Autoregulation Assessment and Measurements
Journal article   Peer reviewed

A Review on Cerebral Autoregulation Assessment and Measurements

Erhard W Lang, Mudaliar Yugan, Jim Lagopoulos, Nick Dorsch, Yam Alan, Jane Griffith and Jamin Mulvey
Australasian Anaesthesia, Vol.2005, pp.161-172
2005
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http://search.informit.com.au/documentSummary;dn=491275364419298;res=IELHEAView
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Abstract

Neurosciences Clinical Sciences cerebral circulation carbonic anhydrase hyperventilation blood circulation intracranial pressure
Cerebral Autoregulation (CA) is the intrinsic ability of the brain to maintain stable cerebral blood flow (CBF) while mean arterial blood pressure (MAP) and cerebral perfusion pressure (CPP) are changing. It constitutes a regulatory mechanism to provide metabolic substrates under physiological and pathological conditions, for instance after neuro-trauma or spontaneous intra-cranial haemorrhage. Constant CBF is regulated by changing arteriolar diameter, which will alter cerebral blood volume (CBV) and, ultimately, intra-cranial pressure (ICP). On the other hand, ICP is the sum of the partial pressures of brain tissue, cerebrospinal fluid (CSF) and CBV.

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