Understanding the influence of lower limb revascularisation and exercise training on arterial and microvascular blood flow in peripheral arterial disease

Digby Krastins

doi:10.25907/00064

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Understanding the influence of lower limb revascularisation and exercise training on arterial and microvascular blood flow in peripheral arterial disease

Thesis

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Understanding the influence of lower limb revascularisation and exercise training on arterial and microvascular blood flow in peripheral arterial disease

Digby Krastins

University of the Sunshine Coast, Queensland

Master of Science, University of the Sunshine Coast, Queensland

2021

DOI:

https://doi.org/10.25907/00064

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Thesis Open Access

Abstract

Human Movement and Sports Science

Cardiovascular Medicine and Haematology

Other Medical and Health Sciences

Surgery

peripheral arterial disease

microcirculation

blood flow

exercise

exercise training

contrast-enhanced ultrasound

Peripheral arterial disease (PAD) is an atherosclerotic disease characterised by decreased leg blood flow and decreased exercise capacity. Low conduit artery blood flow is often assumed to be the primary cause of the decreased exercise capacity. However, low leg blood flow alone does not fully explain the decreased exercise capacity. PAD also leads to reduced muscle microvascular blood flow capacity, although the extent to which muscle microvascular blood flow contributes to the reduced exercise capacity is unknown. Therefore, the relative contributions of leg blood flow and muscle microvascular blood flow to the decreased exercise capacity of patients with PAD were investigated in this thesis.

Details

Title: Understanding the influence of lower limb revascularisation and exercise training on arterial and microvascular blood flow in peripheral arterial disease
Authors: Digby Krastins
Contributors: Christopher Askew (Supervisor) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
Tom Bailey (Supervisor) - University of the Sunshine Coast, Queensland, School of Health and Sport Sciences - Legacy
Awarding institution: University of the Sunshine Coast, Queensland
Degree awarded: Master of Science
Publisher: University of the Sunshine Coast, Queensland
DOI: 10.25907/00064
Organisation Unit: UniSC Clinical Trials Centre; University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; Cancer Research Cluster; School of Health - Sports & Exercise Science; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99533008402621
Output Type: Thesis

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