Incidence and outcomes of perioperative blood transfusions in elective-major abdominal surgery

Fraser Morris

doi:10.25907/00839

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Incidence and outcomes of perioperative blood transfusions in elective-major abdominal surgery

Thesis

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Incidence and outcomes of perioperative blood transfusions in elective-major abdominal surgery

Fraser Morris

University of the Sunshine Coast, Queensland

Master of Science, University of the Sunshine Coast, Queensland

2024

DOI:

https://doi.org/10.25907/00839

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Thesis Open Access

Abstract

Clinical sciences

Medical and biological physics

perioperative

blood

transfusion

surgery

anaemia

MACCE

mortality

complications

patient blood management

postoperative

Elective major abdominal surgery (E-MAS) often presents a challenge to clinicians due to the potential for significant blood loss and resultant anaemia, necessitating perioperative blood transfusions (PBTs) to maintain haemodynamic stability. The impact of PBTs on the management of bleeding and anaemia is a complex and insufficiently explored area for E-MAS patients, particularly as many of these patients are older with complex comorbidities. E-MAS patients as a cohort are nested within the non-cardiac surgery population. However, they have notable differences in underlying disease, and clinical characteristics. Currently, there are no specific transfusion guidelines for E-MAS patients outlined in the Australian National Blood Authority (NBA) Patient Blood Management (PBM) guidelines. Moreover, while transfusions and anaemia have previously been associated with poorer postoperative outcomes in some surgical disciplines, the complex interplay between transfusion and anaemia has not been investigated in E-MAS patients.

Details

Title: Incidence and outcomes of perioperative blood transfusions in elective-major abdominal surgery
Authors: Fraser Morris - University of the Sunshine Coast, Queensland, External
Contributors: Lin Fung (Principal Supervisor) - University of the Sunshine Coast, Queensland, School of Health - Biomedicine
Alison Craswell (Co-Supervisor) - University of the Sunshine Coast, Queensland, School of Health - Nursing
Awarding institution: University of the Sunshine Coast, Queensland
Degree awarded: Master of Science
Publisher: University of the Sunshine Coast, Queensland
DOI: 10.25907/00839
Organisation Unit: Healthy Ageing Research Cluster; School of Health
Language: English
Record Identifier: 991019698902621
Output Type: Thesis

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