Thesis
Development and post-pilot modification of a questionnaire for assessing dietary AGE intake in Australian children with and without type 1 diabetes mellitus
University of the Sunshine Coast, Queensland
Master of Science, University of the Sunshine Coast
2008
DOI:
https://doi.org/10.25907/00388
Abstract
Elevated tissue levels of advanced glycation end products (AGEs) have been associated with complication development in diabetes patients. Recent studies indicate that certain foods are rich sources of AGEs and that dietary AGE intake is associated with serum AGE levels and complication development in type 1 diabetes mellitus (T1DM). Since dietary patterns are established during childhood, AGE monitoring and interventions to reduce dietary AGE intakes may produce long-term health benefits in diabetic children. However, no instruments for the assessment of dietary AGE intake in children currently exist. The primary aim of this research was to develop and pilot a food frequency questionnaire (FFQ) for the assessment of dietary AGE intakes in Australian children (9-16 years of age) with and without T1DM. A 123-item semi-quantitative FFQ comprised of foods known to be high in AGEs was piloted in a group of 18 children with T1DM, and in 21 Non-T1DM children within the same age group. The dietary AGE intake questionnaire (AGE-Q) was developed using a U.S. database of food AGE levels. Dietary AGE intakes tended to be lower in the T1DM children (median 9466 x103 units/day) than the Non-T1DM children (median 16118 x103 units/day). In both groups, the major contributors to dietary AGE intake belonged to the 'meats' and 'extras' food categories, which combined accounted for 80% of dietary AGE intake. T1DM children had a lower AGE intake from fast foods than Non-T1DM children, despite their more frequent fast food consumption. The pilot AGE-Q provided an assessment of dietary AGEs suitable for ranking T1DM and Non-T1DM children according to dietary AGE intakes and identified major dietary sources of AGE. The results of this pilot study were used to refine the questionnaire. After further validation studies, the modified AGE-Q should be a valuable monitoring tool for intervention studies designed to reduce dietary AGE intakes in this age group.
Details
- Title
- Development and post-pilot modification of a questionnaire for assessing dietary AGE intake in Australian children with and without type 1 diabetes mellitus
- Authors
- Rachel C James
- Contributors
- Mark A Holmes (Supervisor)
- Awarding institution
- University of the Sunshine Coast
- Degree awarded
- Master of Science
- Publisher
- University of the Sunshine Coast, Queensland
- DOI
- 10.25907/00388
- Organisation Unit
- School of Health - Biomedicine; School of Health; University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; Centre for Bioinnovation; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99449992702621
- Output Type
- Thesis
- Research Statement
- false
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