Interaction proteomics of the glycine receptor alpha1 and alpha2 subunits: implications for human neurological disease

Dissertation

Doctor of Philosophy, University of the Sunshine Coast, Queensland

2026

DOI:

https://doi.org/10.25907/01093

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Thesis 5.70 MB

Embargoed Access, Embargo ends: 17-Aug-2027 CC BY-NC V4.0

Neurogenetics

Receptors and membrane biology

Glycine receptors

GLRA2

neurodevelopmental disorders

loss-, gain- and alteration-of-function

hyperekplexia/startle disease

proteomics

immunoprecipitation

knockout control

protein-protein interactions

liquid chromatography-tandem mass spectrometry

No abstract available.

Title: Interaction proteomics of the glycine receptor alpha1 and alpha2 subunits: implications for human neurological disease
Authors: Sean Fraser - University of the Sunshine Coast, Queensland, School of Health
Contributors: Robert Harvey (Principal Supervisor) - University of the Sunshine Coast, Queensland, Thompson Institute
Georgia R Kafer (Co-Supervisor) - University of the Sunshine Coast, Queensland, Australian Centre for Pacific Islands Research
Awarding institution: University of the Sunshine Coast, Queensland
Degree awarded: Doctor of Philosophy
DOI: 10.25907/01093
Grants: Unlocking the proteomics of synaptic glycine receptor complexes, DP250101477, Australian Research Council (Australia, Canberra) - ARC
Australian Government Research Training Program (RTP) Scholarship, RTP, Department of Education (Australia, Canberra)
Organisation Unit: School of Health
Language: English
Record Identifier: 991252199602621
Output Type: Dissertation

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