Dissertation
Influence of Age on the Cerebrovascular Responses to Exercise - Understanding the role of blood pressure
University of the Sunshine Coast, Queensland
Doctor of Philosophy, University of the Sunshine Coast, Queensland
2020
DOI:
https://doi.org/10.25907/00026
Abstract
Ageing and age-related cerebrovascular and neurodegenerative diseases, such as stroke and dementia, are associated with a reduction in cerebral blood flow and cerebrovascular function. Exercise is protective against these negative effects of ageing, where an increase in shear stress on the arterial wall, through increased blood flow, is the likely stimulus for enhanced vascular function. Blood pressure plays an important role in contributing to increases in cerebral blood flow. Older adults show a lower increase in cerebral blood flow during exercise, despite a higher increase in blood pressure, compared to younger adults. This suggests a lack of cerebral blood flow responsiveness with changes in arterial blood pressure in older adults. To understand and maximise the cerebral blood flow response to exercise in older adults, the initial aim of this thesis was to investigate the effect of age on cerebrovascular responses during interval and continuous exercise. Furthermore, this thesis aimed to better understand how the cerebral blood flow – blood pressure relationship is affected by age in response to dynamic stimuli. Three experimental studies were conducted to address these objectives.
Details
- Title
- Influence of Age on the Cerebrovascular Responses to Exercise - Understanding the role of blood pressure
- Authors
- Timo Klein
- Contributors
- Christopher Askew (Supervisor) - University of the Sunshine Coast, Queensland, School of Health and Sport Sciences - Legacy
- Awarding institution
- University of the Sunshine Coast, Queensland
- Degree awarded
- Doctor of Philosophy
- Publisher
- University of the Sunshine Coast, Queensland
- DOI
- 10.25907/00026
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; Cancer Research Cluster; School of Health - Sports & Exercise Science; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99472705102621
- Output Type
- Dissertation
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