Dissertation
Genetics of the bacterial (Edwardsiella ictaluri) disease resistance in striped catfish (Pangasianodon hypophthalmus)
University of the Sunshine Coast, Queensland
Doctor of Philosophy, University of the Sunshine Coast, Queensland
2021
DOI:
https://doi.org/10.25907/00102
Abstract
Diseases have caused significant economic losses to the aquaculture industry and striped catfish (Pangasianodon hypophthalmus) is not an exception. A recent estimate of the economic loss for the striped catfish sector is in the order of 48 to 94 million U.S. dollars per annum. Nevertheless, available measures to control bacterial diseases (e.g., Bacillary Necrosis of Pangasius, BNP caused by Edwardsiella ictaluri) are not cost-effective and sustainable. In my PhD study, I have proposed to combine both traditional quantitative genetics and modern genomic approaches to develop disease resistant lines of striped catfish to E. ictaluri.
In the first chapter, I performed a comprehensive quantitative genetic analysis of disease resistant traits of striped catfish to E. ictaluri using a metadata (398,234 individuals comprising 720 full- and half-sib families) over four consecutive challenge tests. The Restricted Maximum Likelihood (REML) analysis using mixed model methodology indicated that there was a substantial genetic variation in the resistance of the breeding population against E. ictaluri (heritability = 0.10 – 0.35). Moreover, the genetic correlations of the E. ictaluri resistance with survival during early growing phase in hapa, survival during grow-out phase from tagging to harvest and marketable body weight were all positive (0.03 – 0.53), suggesting that selection for disease resistance to E. ictaluri may not have detrimental effects on survivals and growth of striped catfish. The high genetic correlation (0.65) between BNP resistance (measured as survival status) and survival time also indicates that these traits could be used as alternative selection criterion in genetic improvement programs for increased disease resistance to E. ictaluri.
Details
- Title
- Genetics of the bacterial (Edwardsiella ictaluri) disease resistance in striped catfish (Pangasianodon hypophthalmus)
- Authors
- Vu Nguyen
- Contributors
- Nguyen Nguyen (Supervisor) - University of the Sunshine Coast, Queensland, GeneCology Research Centre - Legacy
- Awarding institution
- University of the Sunshine Coast, Queensland
- Degree awarded
- Doctor of Philosophy
- Publisher
- University of the Sunshine Coast, Queensland
- DOI
- 10.25907/00102
- Organisation Unit
- Faculty of Science, Health, Education and Engineering; Faculty of Arts, Business and Law; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99584908702621
- Output Type
- Dissertation
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