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Phase change materials as an enabler for malaria detection in low-resource settings
Conference presentation   Peer reviewed

Phase change materials as an enabler for malaria detection in low-resource settings

Dries Vloemans, Francesco Dal Dosso, Carlos Orero, Joanne Macdonald and Jeroen Lammertyn
International Conference on Miniaturized Systems for Chemistry and Life Sciences, 23rd (Basel, Switzerland, 27-Oct-2019 - 31-Oct-2019)
2019
url
https://lirias.kuleuven.be/2854233?limo=0View
Published Version
url
https://microtas2019.org/View
Event Website

Abstract

passive heating phase change materials lab-on-chip point-of-care diagnostics malaria detection
Here, we report the development of a low-cost self-powered heating system for microfluidic devices and its application to detect malaria with integrated recombinase polymerase amplification (RPA) assay. The system couples the exothermic crystallization reaction of supercooled sodium acetate trihydrate (SAT) with a fatty acidbased phase change material (PCM) to ensure controlled and stable on-chip heating. Using this system, 9 malaria plasmids in 10 µL of spiked buffer were detected.

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