Conference presentation
Do large-scale genome changes affect mitochondrial proteomes?
USC Research Conference, 2014 (Sunshine Coast, Australia, 14-Jul-2014–18-Jul-2014)
University of the Sunshine Coast
2014
Abstract
Mitochondria are organelles in eukaryotic cells and are well known for their role as the "powerhouse", where cellular energy is produced. The function of mitochondria, however, extends beyond energy production to metabolism, cell signalling, cell growth, and apoptosis. The efficient function of mitochondria requires coordinated expression of genes from both the nuclear genome and the mitochondrial genome in a cell. It is becoming increasingly clear in recent years that both nuclear and mitochondrial genomes can undergo drastic changes in genome structure, genome size, chromosome number, and gene content, even among closely related eukaryotes. We investigate whether or not large-scale genome changes can impact the function of mitochondria by comparing the mitochondrial proteomes of the human lice and the fruit flies, which differ substantially in both nuclear and mitochondrial genomes. Our preliminary results showed that human lice and fruit flies also differ in their mitochondrial proteomes, indicating genome changes may impact how mitochondria function.
Details
- Title
- Do large-scale genome changes affect mitochondrial proteomes?
- Authors
- Renfu Shao (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringGemma Jeremy (Author)Simon Song (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringTianfang Wang (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringScott F Cummins (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
- Conference details
- USC Research Conference, 2014 (Sunshine Coast, Australia, 14-Jul-2014–18-Jul-2014)
- Publisher
- University of the Sunshine Coast
- Date published
- 2014
- Copyright note
- Copyright © 2014 The Author.
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99448857302621
- Output Type
- Conference presentation
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