Conference poster
ECMO has more profound influence on ciprofloxacin pharmacokinetics in critically ill sheep when compared with healthy sheep
Asia-Pacific Chapter of the Extracorporeal Life Support Organisation (APELSO) Conference, 1st (Beijing, China, 11-Oct-2013–13-Oct-2013)
2013
Abstract
Background / Purpose: Extracoproreal membrane oxygenation (ECMO) is a life saving supportive tool for patients with severe cardiorespiratory failure. However ECMO has a significant impact on pharamcokinetics(PK) of vital drugs that are intended to reverse the pathology which will then result in liberation from ECMO. This mechanistic study aimed to relatively quantify the independent effects of the ECMO device on ciporfloxacin PK.Main conclusion: Critical illness has a major influence on ciprofloxacin PK during ECMO support and the independent effects of ECMO device may not be significant.
Details
- Title
- ECMO has more profound influence on ciprofloxacin pharmacokinetics in critically ill sheep when compared with healthy sheep
- Authors
- K Shekar (Author) - University of QueenslandJ Roberts (Author) - University of QueenslandS Diab (Author) - University of QueenslandK Dunster (Author) - University of QueenslandC McDonald (Author) - University of QueenslandS Chemonges (Author) - University of QueenslandG Simonova (Author) - University of QueenslandS R Foley (Author) - University of QueenslandS Wallis (Author) - University of QueenslandD Platts (Author) - University of QueenslandYoke Lin Fung (Author) - University of QueenslandMaree Smith (Author) - University of QueenslandJ F Fraser (Author) - University of Queensland
- Conference details
- Asia-Pacific Chapter of the Extracorporeal Life Support Organisation (APELSO) Conference, 1st (Beijing, China, 11-Oct-2013–13-Oct-2013)
- Date published
- 2013
- Copyright note
- Copyright © 2013 The Authors. This poster is open access subject to the CC BY Creative Commons 3.0 License.
- Organisation Unit
- School of Health - Biomedicine; University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99448898002621
- Output Type
- Conference poster
- Research Statement
- false
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