Distribution of group A streptococcal virulence genes in group C and G streptococci

M R Davies; David J McMillan; K S Sriprakash; G S Chhatwal

doi:10.1016/j.ics.2005.11.001

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Distribution of group A streptococcal virulence genes in group C and G streptococci

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Distribution of group A streptococcal virulence genes in group C and G streptococci

M R Davies, David J McMillan, K S Sriprakash and G S Chhatwal

International Congress Series, Vol.1289, pp.184-187

Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD), XVIth (Palm Cove, Australia, 25-Sep-2005–29-Sep-2005)

Elsevier BV

2006

DOI: https://doi.org/10.1016/j.ics.2005.11.001

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Abstract

Other Medical and Health Sciences

streptococcus dysgalactiae

streptococcus pyogenes

group G streptococcus

group C streptococcus

virulence array

Streptococcus dysgalactiae, subsp. equisimilis elicit a range of clinical manifestations similar to that of their close genetic relatives, group A streptococcus (GAS). The similarity in disease profiles raises questions as to the degree of genetic similarity between these two human pathogens, particularly in relation to virulence gene repertoires. In this study, we use a group A streptococcal virulence array comprising of 60 genes previously described as GAS virulence factors, and another 159 genes predicted to encode for extracellular proteins to examine the extent of their occurrence in 58 S. dysgalactiae subsp. equisimilis isolates. Between 25% and 50% of the genes represented on the array were present in the S. dysgalactiae subsp. equisimilis isolates. These observations highlight the similar virulence attributes of closely related human pathogenic streptococci.

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Title: Distribution of group A streptococcal virulence genes in group C and G streptococci
Authors: M R Davies (Author) - Queensland Institute of Medical Research
David J McMillan (Author) - German Research Centre for Biotechnology, Germany
K S Sriprakash (Author) - Queensland Institute of Medical Research
G S Chhatwal (Author) - German Research Centre for Biotechnology, Germany
Contributors: K S Sriprakash (Editor)
Publication details: International Congress Series, Vol.1289, pp.184-187
Conference details: Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD), XVIth (Palm Cove, Australia, 25-Sep-2005–29-Sep-2005)
Publisher: Elsevier BV
Date published: 2006
DOI: 10.1016/j.ics.2005.11.001
ISSN: 0531-5131
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99450375502621
Output Type: Conference paper

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