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Thermogelling Polymers and Their History
Book chapter   Peer reviewed

Thermogelling Polymers and Their History

Owh Cally, David James Young and Xian Jun Loh
Biodegradable Thermogels, pp.1-22
Biomaterials Science Series, 2, Royal Society of Chemistry (R S C) Publications
2019
url
https://doi.org/10.1039/9781788012676-00001View
Published Version

Abstract

Organic Chemistry Medicinal and Biomolecular Chemistry
Thermogelling materials have been envisioned as smart biomaterials with significant potential in the biomedical field. Their importance lies at the intersection between two highly medically relevant classes of materials: hydrogels and smart materials. Thermogels possess the high water content and tunable properties of hydrogels and the ability to respond to external temperature change with a simple, physical and reversible sol-to-gel phase transition. Thermogels have been proposed for many uses, including drug delivery, gene delivery and scaffolding for tissue engineering. This chapter provides a short introduction to Pluronics: in particular, thermogelling Pluronic systems, which have been notable players in the biomedical arena since their introduction nearly 70 years ago.

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