Book chapter
Sponge Symbiotic Actinomycetes as Sources of Novel Bioactive Compounds Atlantic and Pacific Ocean Examples
Actinomycetes in Marine and Extreme Environments: Unexhausted Sources for Microbial Biotechnology, pp.1-26
CRC Press
2024
Abstract
Sponges and their associated microbial communities are known to produce chemically diverse metabolites that in nature serve as functional compounds required by the host. These compounds were also found to carry therapeutic importance as antimicrobial, anticancer and antioxidant agents. Actinomycetes are well known for their capability to produce many biologically active compounds, especially those from the genus Streptomyces. Due to the high demand for novel antibacterial drugs to combat antibiotic-resistant bacteria, finding novel bioactive compounds produced by actinomycetes that are isolated from extreme or underexplored habitats, is of importance and may pave the way to novel drug discovery. Novel or rare species of species of actinomycetes from marine sponges with altered biosynthetic pathways to adapt such environments might also provide novel scaffold molecules for drugs. Therefore, isolation of bioactive compounds from sponge symbiotic actinomycetes and getting information from their genomes on their biosynthetic genes are of importance. The chapter thus provides an overview on the sponge symbiotic and bioactive actinomycetes with examples from Atlantic and Pacific Oceans.
Details
- Title
- Sponge Symbiotic Actinomycetes as Sources of Novel Bioactive Compounds Atlantic and Pacific Ocean Examples
- Authors
- Asmaa Boufridi (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and EngineeringCandice M. Brinkmann (Author) - Griffith UniversityChandra Risdian (Author) - Helmholtz Centre for Infection ResearchJoachim Wink (Author) - Helmholtz Centre for Infection ResearchD. İpek Kurtböke (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and Engineering
- Contributors
- D. İpek Kurtböke (Editor)
- Publication details
- Actinomycetes in Marine and Extreme Environments: Unexhausted Sources for Microbial Biotechnology, pp.1-26
- Publisher
- CRC Press
- DOI
- 10.1201/9780429293948-1; 10.1201/9780429293948
- ISBN
- 9780429293948
- Organisation Unit
- School of Science and Engineering - Legacy; GeneCology Research Centre - Legacy; School of Health - Biomedicine; School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99992782302621
- Output Type
- Book chapter
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