Chlamydia

L M Hafner; Peter Timms

doi:10.1016/B978-0-12-391059-2.00015-2

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Chlamydia

L M Hafner and Peter Timms

Sexually Transmitted Diseases: Vaccines, Prevention and Control, 2nd Edition, pp.369-410

Elsevier Inc., 2nd Edition

2013

DOI: https://doi.org/10.1016/B978-0-12-391059-2.00015-2

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Abstract

Microbiology

Chlamydia trachomatis

vaccine development

Chlamydial infections of humans can cause blindness and infertility as a result of diseases such as keratoconjunctivitis (trachoma), urethritis and cervicitis. However, in greater than half of all chlamydial diseases in males and females there are no signs or symptoms of infection. Chlamydia trachomatis is the causative bacterial organism responsible for the global estimate of 40.6 million people currently suffering with active trachoma and for the five million new cases of sexually transmitted infections each year in the United States of America. Even though antibiotics are available to treat Chlamydia, the incidence of each of these primarily asymptomatic infections continues to increase. In this Chapter we review the current knowledge of C.trachomatis including clinicial diseases and sequelae, the chlamydial developmental cycle in vivo, immunobiology and immune responses to infections, chlamydial genomics and vaccine development.

Details

Title: Chlamydia
Authors: L M Hafner (Author) - Queensland University of Technology
Peter Timms (Author) - Queensland University of Technology
Contributors: L R Stanberry (Editor)
S L Rosenthal (Editor)
Publication details: Sexually Transmitted Diseases: Vaccines, Prevention and Control, 2nd Edition, pp.369-410
Publisher: Elsevier Inc.
Date published: 2013
Edition: 2nd Edition
DOI: 10.1016/B978-0-12-391059-2.00015-2
ISBN: 9780123910592
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99448936502621
Output Type: Book chapter

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